Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.39 |
| ▸ | SLC13A2 | Q13183 | 1/20 | 0.39 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15545023 | 0.85 | SLC13A5 (0.40) | SLC13A5SLC13A2SLC13A3PIK3CAALDH1A1 | |
| SCHEMBL3417608 | 0.81 | SLC13A5 (0.40) | SLC13A5SLC13A2SLC13A3ALDH1A1TSHR | |
| SCHEMBL6498283 | 0.80 | PPARG (0.41) | ALDH1A1TSHRNPSR1KDM4EHPGD | |
| SCHEMBL15545351 | 0.77 | ATM (0.43) | ALDH1A1SMN1; SMN2POLBMEN1NPC1 | |
| SCHEMBL15545354 | 0.77 | ATM (0.43) | ALDH1A1SMN1; SMN2POLBMEN1NPC1 | |
| SCHEMBL5034488 | 0.75 | ALDH1A1 (0.51) | ALDH1A1TSHRNPSR1SMN1; SMN2POLB | |
| SCHEMBL6425131 | 0.75 | MAOB (0.45) | ALDH1A1NPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL26101402 | 0.74 | ALDH1A1 (0.45) | PIK3CAALDH1A1TSHRSMN1; SMN2POLB | |
| SCHEMBL26101902 | 0.74 | NPC1 (0.43) | SLC13A5SLC13A2SLC13A3PIK3CAALDH1A1 | |
| SCHEMBL15719149 | 0.73 | FDPS (0.40) | PIK3CAALDH1A1TSHRKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |