Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495742 | 0.80 | CNR1 (0.47) | L3MBTL1ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL6505396 | 0.80 | SLC13A5 (0.39) | ALDH1A1TSHRNPSR1KDM4EHPGD | |
| SCHEMBL6504884 | 0.77 | FAAH (0.44) | L3MBTL1LMNANPSR1FAAHGAA | |
| SCHEMBL10325615 | 0.72 | FAAH (0.50) | ALDH1A1TSHRLMNAFAAHHPGD | |
| SCHEMBL15738726 | 0.70 | SMN1; SMN2 (0.46) | L3MBTL1ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL30931653 | 0.70 | FAAH (0.41) | PPARGL3MBTL1ALDH1A1TSHRLMNA | |
| SCHEMBL29462477 | 0.70 | TSHR (0.46) | PPARGL3MBTL1EGFRKDRALDH1A1 | |
| SCHEMBL6498349 | 0.69 | TSHR (0.60) | ALDH1A1TSHRNPSR1KDM4EGAA | |
| SCHEMBL3416633 | 0.68 | TSHR (0.46) | L3MBTL1ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL2484382 | 0.68 | LMNA (0.45) | L3MBTL1ALDH1A1TSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |