Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.46 |
| ▸ | DHODH | Q02127 | 6/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | PLAT | P00750 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505463 | 0.90 | HDAC6 (0.45) | HDAC6DHODHF2F10PLG | |
| SCHEMBL6510661 | 0.85 | F2 (0.46) | HDAC6AMY1AF2F10PLG | |
| SCHEMBL6506681 | 0.82 | HDAC6 (0.47) | HDAC6PLAUPRSS1HDAC3HDAC1 | |
| SCHEMBL23540846 | 0.82 | HDAC6 (0.36) | HDAC6F2F10PLGPLAU | |
| SCHEMBL1841109 | 0.82 | NR4A2 (0.52) | HDAC6PLAUPRSS1HDAC3HDAC1 | |
| SCHEMBL20982814 | 0.81 | HDAC6 (0.48) | HDAC6PLAUPRSS1HDAC3HDAC1 | |
| SCHEMBL6511656 | 0.81 | AMY1A (0.42) | HDAC6AMY1AF2F10PLG | |
| SCHEMBL6510551 | 0.79 | F2 (0.55) | HDAC6F2F10PLGPLAU | |
| SCHEMBL6503801 | 0.78 | HPSE (0.42) | HDAC6HDAC3HDAC1HDAC8NPC1 | |
| SCHEMBL6506820 | 0.77 | F2 (0.44) | HDAC6AMY1AF2F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050148646-A1 | Dicationic triaryl analogs as anti-protozoan agents | BOYKIN DAVID W (US) | 2005-07-07 | — | — | US | claimed |
| US-20050148646-A1 | Dicationic triaryl analogs as anti-protozoan agents | BOYKIN DAVID W (US) | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148646-A1 | Dicationic triaryl analogs as anti-protozoan agents | DDT, DDC, DARS1 | HDAC6 466/4885DHODH 4/4885AMY1A 4670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.