Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507599 | 0.82 | GSK3B (0.48) | POLBHPGD | |
| SCHEMBL6507602 | 0.82 | GSK3B (0.48) | POLBHPGD | |
| SCHEMBL6505495 | 0.79 | ALDH1A1 (0.46) | KMT2ATSHRMAPTALDH1A1POLB | |
| SCHEMBL6533265 | 0.77 | PTAFR (0.46) | KMT2ATSHRMAPTALDH1A1POLB | |
| SCHEMBL5107391 | 0.76 | KMT2A (0.43) | KMT2ATSHRMAPTALDH1A1HTR1A | |
| SCHEMBL6532625 | 0.76 | MAPT (0.40) | KMT2AMAPTALDH1A1POLBNOTUM | |
| SCHEMBL6512702 | 0.76 | P2RX4 (0.35) | KMT2ATSHRALDH1A1HPGDLMNA | |
| SCHEMBL6528104 | 0.74 | PPARG (0.43) | KMT2ATSHRMAPTALDH1A1HPGD | |
| SCHEMBL21729164 | 0.72 | KMT2A (0.52) | KMT2ATSHRMAPTALDH1A1HTR1A | |
| SCHEMBL6532464 | 0.72 | PPARA (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | disclosed |