SCHEMBL650572

SCHEMBL650572

O=C(c1ccccc1F)C(O)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 8/20 0.68
CES1 P23141 8/20 0.68
LMNA P02545 3/20 0.57
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
MAPK1 P28482 1/20 0.52
ALDH1A1 P00352 2/20 0.48
ALOX15 P16050 1/20 0.48
NPSR1 Q6W5P4 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KDM4E B2RXH2 1/20 0.45
PTPN1 P18031 1/20 0.44
ERCC5 P28715 1/20 0.44
FEN1 P39748 1/20 0.44
GAA P10253 1/20 0.44
SRC P12931 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30013497 1.00 CES2 (0.68) CES2CES1LMNAMEN1KMT2A
SCHEMBL4935172 0.87 CES2 (0.68) CES2CES1LMNAMEN1KMT2A
SCHEMBL30716847 0.86 ALB (0.58) CES2CES1LMNAMEN1KMT2A
SCHEMBL8800484 0.86 CES2 (0.51) CES2CES1LMNAMEN1KMT2A
SCHEMBL28868999 0.84 CES2 (0.50) CES2CES1LMNAMEN1KMT2A
SCHEMBL28956589 0.84 CES2 (0.50) CES2CES1LMNAMEN1KMT2A
SCHEMBL28137004 0.84 CES2 (0.50) CES2CES1LMNAMEN1KMT2A
SCHEMBL8800486 0.83 CES2 (0.49) CES2CES1LMNAMEN1KMT2A
SCHEMBL10818690 0.82 ALDH1A1 (0.59) CES2CES1LMNAMEN1KMT2A
SCHEMBL7414865 0.81 CES2 (1.00) CES2CES1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 554 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110372653-A A kind of selenizing benzofuran compound and its synthetic method 温州大学 2019-10-25 CN claimed
CN-109928945-A A kind of 1- bromine dibenzofurans and its synthetic method 西安欧得光电材料有限公司 2019-06-25 CN claimed
CN-109467662-A A kind of RTM type boron bakelite resin and preparation method thereof 北京玻钢院复合材料有限公司 2019-03-15 CN claimed
CN-109456571-A A kind of heat molten type boron bakelite resin and preparation method thereof 北京玻钢院复合材料有限公司 2019-03-12 CN claimed
CN-108947888-A A method of palladium chtalyst synthesis 3- replaces isoindolinone in water phase 南京理工大学 2018-12-07 CN claimed
CN-108440599-A The Pd-PEPPSI-NHC complexs and purposes of series base group modification containing high steric hindrance 天津师范大学 2018-08-24 CN claimed
CN-105753835-B Method for synthesizing 2- (4-fluorophenyl) thiophene 黑龙江鑫创生物科技开发有限公司 2018-06-12 CN claimed
CN-108017624-A The structure and its synthetic method of puerarin derivate 潘嘉慧 2018-05-11 CN claimed
CN-108004372-A High calcium aluminium slag ball and preparation method thereof 天津基纳科技发展有限公司 2018-05-08 CN claimed
CN-104628653-B The method of synthesizing rosuvastatin spit of fland calcium key intermediate 湖北益泰药业有限公司 2018-04-03 CN claimed
CN-1974616-A Polyacrylate compound and its prepn process and application in liquid crystal composition SHANGHAI FUXIAN PHOTOELECTRONI (CN) 2007-06-06 CN claimed
CN-1911880-A Multifluoro substituted diphenyl acetylene derivative, composition containing multifluoro substituted diphenyl acetylene derivatire, its preparation method and use SHIJIAZHUANG YONGSHENGHUAQING (CN) 2007-02-14 CN claimed
CN-1273473-C 3,5-difluoro-4-cyan benzene boric acid ester compound, preparing process thereof and application in liquid crystal composition SHIJIAZHUANG YONGSHENG HUASING (CN) 2006-09-06 CN claimed
CN-1733676-A 4-(4-n-alkyl)phenyl-3,5(or2,3)-difluoro-1',1'-difluorobenzyl-3,4,5-trifluorophenyl ether preparation method SHANGHAI KANGPENG CHEMICAL CO (CN) 2006-02-15 CN claimed
CN-1504470-A 3,5-difluoro-4-cyan benzene boric acid ester compound, preparing process thereof and application in liquid crystal composition 石家庄实力克液晶材料有限公司 2004-06-16 CN claimed
WO-2002067304-A1 A METHOD OF FORMING RESIST PATTERNS IN A SEMICONDUCTOR DEVICE AND A SEMICONDUCTOR WASHING LIQUID USED IN SAID METHOD HYON MAN-SOK (KR) 2002-08-29 WO claimed
EP-0788314-B1 NONDIGESTIBLE FAT COMPOSITIONS CONTAINING DIVERSELY ESTERIFIED POLYOL POLYESTERS FOR PASSIVE OIL LOSS CONTROL PROCTER & GAMBLE (US) 2001-09-12 EP claimed
EP-0788314-A1 NONDIGESTIBLE FAT COMPOSITIONS CONTAINING DIVERSELY ESTERIFIED POLYOL POLYESTERS FOR PASSIVE OIL LOSS CONTROL THE PROCTER & GAMBLE COMPANY (US) 1997-08-13 EP claimed
US-5480667-A CONTAING NONDIGESTIBLE SOLID POLYOL ESTERS OF SPECIFIED CARBON CHAIN LENGTH FATTY ACID DISPERSED IN LIQUID NONDIGESTIBLE OIL; POTATO CHIPS CORRIGAN PATRICK J (US) 1996-01-02 US claimed
WO-1994009639-A1 NONDIGESTIBLE FAT COMPOSITIONS CONTAINING DIVERSELY ESTERIFIED POLYOL POLYESTERS FOR PASSIVE OIL LOSS CONTROL THE PROCTER & GAMBLE COMPANY (US) 1994-05-11 WO claimed