Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 7/20 | 0.49 |
| ▸ | CES1 | P23141 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL650572 | 0.83 | CES2 (0.68) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL30013497 | 0.83 | CES2 (0.68) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL4935172 | 0.82 | CES2 (0.68) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL8799603 | 0.81 | FABP3 (0.49) | CES2CES1LMNAMAPK1ALDH1A1 | |
| SCHEMBL30716847 | 0.81 | ALB (0.58) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL27675807 | 0.80 | AKR1C3 (0.44) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL28956589 | 0.79 | CES2 (0.50) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL28137004 | 0.79 | CES2 (0.50) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL28868999 | 0.79 | CES2 (0.50) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL8801412 | 0.78 | ALDH1A1 (0.49) | CES2CES1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772601-A1 | 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | disclosed |