Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.61 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 9/20 | 0.44 |
| ▸ | RAB9A | P51151 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5643986 | 0.84 | NR1H4 (0.51) | ACHEAOC3PIK3CGNPC1RAB9A | |
| SCHEMBL77062 | 0.84 | NPC1 (0.61) | AOC3NPC1RAB9AMAPTHPGD | |
| SCHEMBL21914357 | 0.82 | NPC1 (0.50) | ACHEAOC3PIK3CGNPC1RAB9A | |
| SCHEMBL26262564 | 0.82 | AOC3 (0.50) | ACHEAOC3PIK3CGNPC1RAB9A | |
| SCHEMBL19625438 | 0.82 | NR1H4 (0.56) | AOC3PIK3CGNPC1RAB9AMAPT | |
| SCHEMBL77636 | 0.81 | NR1H4 (0.57) | AOC3NPC1RAB9AMAPTHPGD | |
| SCHEMBL15132141 | 0.80 | RAB9A (0.61) | AOC3NPC1RAB9AMAPTHPGD | |
| SCHEMBL77091 | 0.79 | LMNA (0.59) | AOC3NPC1RAB9AMAPTHPGD | |
| SCHEMBL77575 | 0.79 | NPC1 (0.58) | AOC3NPC1RAB9AMAPTHPGD | |
| SCHEMBL20567552 | 0.79 | AOC3 (0.44) | ACHEAOC3PIK3CGNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107456-A1 | Substituted pyrazolines for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2005-05-19 | — | — | US | disclosed |
| EP-1467971-A1 | SUBSTITUTED PYRAZOLINES FOR USE AS PESTICIDES | Bayer CropScience AG (DE) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003059887-A1 | SUBSTITUTED PYRAZOLINES FOR USE AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003016293-A1 | OXADIAZOLYL AND THIADIAZOLYL BENZOYL UREAS AND THE USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107456-A1 | Substituted pyrazolines for use as pesticides | DDT, ACHE, CHRM1 | ACHE 2/4885AOC3 486/4885BCHE 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.