Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506203 | 1.00 | ADRB2 (0.52) | ADRB2CHRM3ADRB1ADRB3MEN1 | |
| SCHEMBL6515169 | 0.87 | ADRB2 (0.53) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL6515181 | 0.87 | ADRB2 (0.53) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL6530357 | 0.86 | ADRB2 (0.47) | ADRB2ADRB1MEN1KMT2A | |
| SCHEMBL6504599 | 0.86 | ADRB2 (0.52) | ADRB2CHRM3ADRB1 | |
| SCHEMBL6531802 | 0.85 | ADRB2 (0.49) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6508746 | 0.85 | ADRB2 (0.52) | ADRB2CHRM3ADRB1 | |
| SCHEMBL3917083 | 0.84 | ADRB2 (0.45) | ADRB2ADRB1MEN1KMT2A | |
| SCHEMBL6511853 | 0.82 | ADRB2 (0.50) | ADRB2CHRM3ADRB1 | |
| SCHEMBL6506911 | 0.81 | ADRB2 (0.52) | ADRB2CHRM3ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092841-A1 | COMPOUNDS HAVING BETA-AGONIST ACTIVITY | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | disclosed |