Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6515195 | 0.87 | ADRB2 (0.45) | ADRB2ADRB1CHRM4CCR1 | |
| SCHEMBL3915206 | 0.86 | ADRB2 (0.43) | ADRB2ADRB1CHRM4CCR1 | |
| SCHEMBL6515181 | 0.83 | ADRB2 (0.53) | ADRB2CHRM3ADRB1 | |
| SCHEMBL6515169 | 0.83 | ADRB2 (0.53) | ADRB2CHRM3ADRB1 | |
| SCHEMBL6506207 | 0.82 | ADRB2 (0.52) | ADRB2CHRM3ADRB1 | |
| SCHEMBL6506203 | 0.82 | ADRB2 (0.52) | ADRB2CHRM3ADRB1 | |
| SCHEMBL6504599 | 0.82 | ADRB2 (0.52) | ADRB2CHRM3ADRB1 | |
| SCHEMBL6508746 | 0.81 | ADRB2 (0.52) | ADRB2CHRM3ADRB1 | |
| SCHEMBL6491888 | 0.81 | LMNA (0.42) | ADRB2ADRB1CHRM4CCR1 | |
| SCHEMBL6531802 | 0.80 | ADRB2 (0.49) | ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092841-A1 | COMPOUNDS HAVING BETA-AGONIST ACTIVITY | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | disclosed |