Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 15/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507412 | 0.88 | KDM4E (0.49) | ADRB2KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL3915463 | 0.86 | KDM4E (0.49) | ADRB2KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL6506207 | 0.85 | ADRB2 (0.52) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6506203 | 0.85 | ADRB2 (0.52) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6515181 | 0.84 | ADRB2 (0.53) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6515169 | 0.84 | ADRB2 (0.53) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6504599 | 0.84 | ADRB2 (0.52) | ADRB2ADRB1 | |
| SCHEMBL6508746 | 0.82 | ADRB2 (0.52) | ADRB2ADRB1 | |
| SCHEMBL6482712 | 0.82 | KDM4E (0.47) | ADRB2KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL6511853 | 0.80 | ADRB2 (0.50) | ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092841-A1 | COMPOUNDS HAVING BETA-AGONIST ACTIVITY | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | disclosed |