Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24123559 | 0.86 | IAPP (0.50) | KDM4ECYP1A2MAPTP2RX7FFAR1 | |
| SCHEMBL575046 | 0.85 | KDM4E (0.62) | KDM4ECYP1A2MAPTP2RX7FFAR1 | |
| SCHEMBL20520324 | 0.84 | P2RX7 (0.47) | KDM4ECYP1A2MAPTP2RX7FFAR1 | |
| Hydrochloric Acid SCHEMBL3725590 | 0.84 | KDM4E (0.61) | KDM4ECYP1A2MAPTP2RX7FFAR1 | |
| SCHEMBL12530239 | 0.83 | IAPP (0.53) | KDM4ECYP1A2MAPTP2RX7FFAR1 | |
| SCHEMBL30178346 | 0.80 | CYP4F2 (0.60) | KDM4ECYP1A2MAPTL3MBTL1P2RX7 | |
| SCHEMBL8664219 | 0.80 | CYP4F2 (0.60) | KDM4ECYP1A2MAPTL3MBTL1P2RX7 | |
| SCHEMBL2561240 | 0.79 | FFAR1 (0.54) | KDM4ECYP1A2MAPTFFAR1ALDH1A1 | |
| SCHEMBL19460839 | 0.79 | KDM4E (0.46) | KDM4ECYP1A2MAPTNPSR1FFAR1 | |
| SCHEMBL7387417 | 0.79 | SHMT2 (0.54) | KDM4ECYP1A2MAPTNPSR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005123727-A1 | 3-ARYL-3-HYDROXY- AND 3-ARYL-3-OXOPROPIONIC ACID ESTERS AS FUNGICIDES | CROPSOLUTION, INC. (US) | 2005-12-29 | — | — | WO | disclosed |