SCHEMBL575046

SCHEMBL575046

Cc1ncccc1CC(=O)O

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.62
CYP1A2 P05177 1/20 0.62
MAPT P10636 1/20 0.62
AKR1B1 P15121 1/20 0.48
P2RX7 Q99572 1/20 0.47
FFAR1 O14842 1/20 0.46
CYP2C9 P11712 1/20 0.45
NAMPT P43490 1/20 0.45
PTGDR2 Q9Y5Y4 4/20 0.43
NAPRT Q6XQN6 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PTGS2 P35354 1/20 0.42
EGLN1 Q9GZT9 1/20 0.42
SLC22A12 Q96S37 1/20 0.41
DPP4 P27487 1/20 0.41
MKNK1 Q9BUB5 1/20 0.40
MKNK2 Q9HBH9 1/20 0.40
CYP19A1 P11511 1/20 0.40
PTGS1 P23219 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3725590 0.98 KDM4E (0.61) KDM4ECYP1A2MAPTAKR1B1P2RX7
SCHEMBL6506265 0.85 KDM4E (0.50) KDM4ECYP1A2MAPTP2RX7FFAR1
SCHEMBL13568063 0.85 P2RX7 (0.47) KDM4ECYP1A2MAPTP2RX7FFAR1
SCHEMBL999250 0.83 P2RX7 (0.50) KDM4ECYP1A2MAPTP2RX7FFAR1
SCHEMBL14676404 0.83 PTGDR2 (0.46) KDM4ECYP1A2MAPTAKR1B1FFAR1
SCHEMBL28239019 0.82 CTNNB1 (0.49) KDM4ECYP1A2MAPTP2RX7CYP2C9
SCHEMBL20037256 0.82 PAM (0.50) KDM4ECYP1A2MAPTP2RX7FFAR1
Acetic Acid SCHEMBL28688767 0.81 P2RX7 (0.47) KDM4ECYP1A2MAPTP2RX7FFAR1
SCHEMBL8570752 0.80 P2RX7 (0.47) KDM4ECYP1A2MAPTP2RX7FFAR1
SCHEMBL14678422 0.80 P2RX7 (0.47) KDM4ECYP1A2MAPTP2RX7FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107710462-A Electrochemical hydrogen storage electrode and battery 巴斯夫公司 2018-02-16 CN claimed
CN-107615556-A Electrolyte and metal hydride battery 巴斯夫公司 2018-01-19 CN claimed
CN-107004912-A Electrolyte and metal hydride battery 巴斯夫公司 2017-08-01 CN claimed
CN-119259264-A Method for recovering and extracting noble metal from mineral dressing tailings 江西一元再生资源有限公司 2025-01-07 CN disclosed
WO-2024174680-A1 BUILDING BLOCKS FOR DIFFICULT PEPTIDE SYNTHESIS AND METHOD OF MAKING THEREOF VERSITECH LIMITED (CN) 2024-08-29 WO disclosed
US-11885818-B2 Reagent for mass spectrometry ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2024-01-30 US disclosed
CN-117430501-A Method and device for recycling waste solvent of medicinal picoline 天津华信化工技术有限公司 2024-01-23 CN disclosed
CN-219963978-U Recycling device for waste medicinal picoline solvent 天津华信化工技术有限公司 2023-11-07 CN disclosed
US-20230348369-A1 NAMPT MODULATORS CYTOKINETICS, INC. 2023-11-02 US disclosed
EP-4233865-A2 ARYL-ANILINE AND HETEROARYL-ANILINE COMPOUNDS FOR TREATMENT OF SKIN CANCERS NFlection Therapeutics, Inc. (US) 2023-08-30 EP disclosed
EP-3826995-A1 REAGENT FOR MASS SPECTROMETRY F. Hoffmann-La Roche AG (CH) 2021-06-02 EP disclosed
US-4826531-A ACRYLIC ACID PYRIDINE DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-05-02 US disclosed
EP-0243012-A2 Pyridyl-acrylic acid ester derivatives, process for their preparation and their use as fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-10-28 EP disclosed
EP-0060144-A2 Cephalosporin antibiotics ELI LILLY AND COMPANY (US) 1982-09-15 EP disclosed
US-4225715-A Preparation of 3-amino(or carbamyl)-5-(pyridinyl)-2(1H)-pyridinones STERLING DRUG INC. (US) 1980-09-30 US disclosed
US-4199586-A Di-(lower-alkyl) N-[1,2-dihydro-2-oxo-5-(pyridinyl)-3-pyridinyl]amino-methylanemalonates STERLING DRUG INC. (US) 1980-04-22 US disclosed
US-4137233-A 1,2-Dihydro-2-oxo-5-(pyridinyl)nicotinamides STERLING DRUG INC. (US) 1979-01-30 US disclosed
US-4107315-A 5-(Pyridinyl)-2(1H)-pyridinones STERLING DRUG INC. (US) 1978-08-15 US disclosed
US-4072746-A CARDIOTONIC AGENTS STERLING DRUG INC. (US) 1978-02-07 US disclosed
US-4004012-A 3-Cyano-5-(pyridinyl)-2(1H)-pyridinones STERLING DRUG INC. (US) 1977-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348369-A1 NAMPT MODULATORS NAMPT, NNT, NAPRT KDM4E 2846/4885CYP1A2 1682/4885MAPT 582/4885
US-11885818-B2 Reagent for mass spectrometry SRMS, PTMS, MMAB KDM4E 1155/4885CYP1A2 442/4885MAPT 3790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.