Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 19/20 | 0.59 |
| ▸ | ITGA4 | P13612 | 16/20 | 0.59 |
| ▸ | ITGB7 | P26010 | 14/20 | 0.59 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5783429 | 0.91 | ITGB1 (0.64) | ITGB1ITGA4ITGB7ITGA5ITGB3 | |
| SCHEMBL5784609 | 0.88 | ITGA4 (0.68) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5786242 | 0.87 | ITGA4 (0.62) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5785489 | 0.87 | ITGA4 (0.64) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5785174 | 0.86 | ITGA4 (0.70) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5782050 | 0.86 | ITGA4 (0.65) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5787036 | 0.84 | ITGA4 (0.68) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1222489 | 0.84 | ITGA4 (0.74) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1222491 | 0.84 | ITGA4 (0.74) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5784261 | 0.84 | ITGA4 (0.65) | ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855843-B2 | Inhibitors of α4 mediated cell adhesion | TANABE SEIYAKU CO., LTD. (JP) | 2005-02-15 | — | — | US | disclosed |
| US-20030191118-A1 | Inhibitors of alpha4 mediated cell adhesion | TANABE SEIYAKU CO., LTD. | 2003-10-09 | — | — | US | disclosed |
| US-6521666-B1 | Inhibitors of α4 mediated cell adhesion | TANABE SEIYAKU CO., LTD. (JP) | 2003-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191118-A1 | Inhibitors of alpha4 mediated cell adhesion | ITGB4, ITGA4, VCAM1 | ITGB1 7/4885ITGA4 2/4885ITGB7 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.