Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL6506374

CC1C(C(N)=O)CCCN1C.O=C(O)C(F)(F)F

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.41
DPP8 Q6V1X1 4/20 0.34
DPP4 P27487 3/20 0.34
DPP7 Q9UHL4 2/20 0.34
DRD2 P14416 1/20 0.34
DRD1 P21728 1/20 0.34
CHRNB2 P17787 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA4 P43681 1/20 0.31
CHRNB3 Q05901 1/20 0.31
CHRNA6 Q15825 1/20 0.31
BCHE P06276 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15322998 0.88 EPHX1 (0.50) EPHX1DPP8DPP4DPP7BCHE
Trifluoroacetic Acid SCHEMBL3275665 0.79 CYP3A4 (0.37) DPP8DPP4DPP7DRD2DRD1
Trifluoroacetic Acid SCHEMBL30408711 0.79 CYP3A4 (0.37) DPP8DPP4DPP7DRD2DRD1
Trifluoroacetic Acid SCHEMBL30407660 0.79 CYP3A4 (0.37) DPP8DPP4DPP7DRD2DRD1
Trifluoroacetic Acid SCHEMBL7259177 0.78 DPP4 (0.40) DPP8DPP4DPP7DRD2DRD1
SCHEMBL21296532 0.77 EPHX1 (0.43) EPHX1BCHE
SCHEMBL15800379 0.77 EPHX1 (0.43) EPHX1BCHE
SCHEMBL23081228 0.76 ALDH1A1 (0.36) CHRNB2CHRNA4
SCHEMBL16759353 0.76 ALDH1A1 (0.36) CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL2146244 0.76 EPHX1 (0.42) EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4138824-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS Anovia Biosciences, Inc. (US) 2023-03-01 EP disclosed
US-20050009843-A1 Medicine for inhibiting drug elimination pump TRINE PHARMACEUTICALS, INC. 2005-01-13 US disclosed
EP-1389463-A1 MEDICINE FOR INHIBITING DRUG ELIMINATION PUMP DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-02-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050009843-A1 Medicine for inhibiting drug elimination pump ABCB11, ATP6AP1, HRH2 EPHX1 1332/4885DPP8 2778/4885DPP4 1139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.