Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27926986 | 0.83 | RECQL (0.38) | HRH3CHRNB2CHRNA4CHRNA3CHRNA5 | |
| Oxalic Acid SCHEMBL5857369 | 0.81 | GAA (0.44) | HRH3GAAHPGDRECQL | |
| Trifluoroacetic Acid SCHEMBL28109182 | 0.81 | DPP4 (0.46) | DPP4DPP8DPP7GAAHPGD | |
| Acetic Acid SCHEMBL9033618 | 0.79 | GAA (0.43) | HRH3GAAHPGDRECQL | |
| Trifluoromethanesulfonic Acid SCHEMBL30212965 | 0.78 | ACHE (0.36) | DRD2DRD1HRH3 | |
| Trifluoroacetic Acid SCHEMBL30408711 | 0.78 | CYP3A4 (0.37) | DPP4DPP8DRD2DRD1DPP7 | |
| Trifluoroacetic Acid SCHEMBL3275665 | 0.78 | CYP3A4 (0.37) | DPP4DPP8DRD2DRD1DPP7 | |
| Trifluoroacetic Acid SCHEMBL27713091 | 0.78 | DRD2 (0.43) | DPP4DPP8DRD2DRD1HRH3 | |
| Trifluoroacetic Acid SCHEMBL30407660 | 0.78 | CYP3A4 (0.37) | DPP4DPP8DRD2DRD1DPP7 | |
| Trifluoroacetic Acid SCHEMBL6506374 | 0.78 | EPHX1 (0.41) | DPP4DPP8DRD2DRD1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669721-B | Anticholinergic agent | 宁康瑞珠生物制药(珠海)有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-116669721-A | Anticholinergic agent | 宁康瑞珠生物制药(珠海)有限公司 | 2023-08-29 | — | — | CN | disclosed |
| US-6545013-B2 | Of squaric acids; inhibit the binding of integrins to their ligands and are of use in the prophylaxis and treatment of immuno or inflammatory disorders or disorders involving the inappropriate growth or migration of cells. | CELLTECH R&D LIMITED (GB) | 2003-04-08 | — | — | US | disclosed |
| EP-1286995-A1 | 2,7-NAPHTHYRIDINE DERIVATIVES | Celltech R&D Limited (GB) | 2003-03-05 | — | — | EP | disclosed |
| US-20020115684-A1 | 2, 7-naphthyridine derivatives | CELLTECH R&D, LTD. (GB) | 2002-08-22 | — | — | US | disclosed |
| WO-2001092256-A1 | 2,7-NAPHTHYRIDINE DERIVATIVES | CELLTECH R & D LIMITED (GB) | 2001-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115684-A1 | 2, 7-naphthyridine derivatives | VCAM1, ICAM1, SELL | DPP4 3954/4885DPP8 4128/4885DRD2 1502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.