SCHEMBL6506506

SCHEMBL6506506

Oc1ccccc1-c1cccc2c1oc1ccccc12

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.76
MAOA P21397 3/20 0.54
AKR1C3 P42330 1/20 0.50
AKR1C2 P52895 1/20 0.50
AKR1C1 Q04828 1/20 0.50
KDM4E B2RXH2 2/20 0.46
MEN1 O00255 2/20 0.46
CYP3A4 P08684 2/20 0.46
MAPT P10636 2/20 0.46
HPGD P15428 2/20 0.46
RECQL P46063 2/20 0.46
KMT2A Q03164 2/20 0.46
HSD17B10 Q99714 2/20 0.46
TP53 P04637 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
CYP2C19 P33261 1/20 0.46
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10945864 0.88 ALOX5 (0.68) ALOX5MAOAKDM4EMEN1CYP3A4
SCHEMBL16633881 0.86 ALOX5 (0.67) ALOX5MAOAKDM4EMEN1CYP3A4
SCHEMBL12996513 0.86 ALOX5 (0.66) ALOX5MAOAKDM4EMEN1CYP3A4
SCHEMBL5028273 0.86 ALOX5 (0.66) ALOX5MAOAKDM4EMEN1CYP3A4
SCHEMBL431458 0.86 ALOX5 (0.66) ALOX5MAOAKDM4EMEN1CYP3A4
SCHEMBL430138 0.86 ALOX5 (0.66) ALOX5MAOAKDM4EMEN1CYP3A4
SCHEMBL17974232 0.84 ALOX5 (0.69) ALOX5MAOAKDM4EMEN1CYP3A4
SCHEMBL1301738 0.84 MAOA (0.72) ALOX5MAOAKDM4EMEN1CYP3A4
SCHEMBL1587857 0.84 ALOX5 (0.81) ALOX5MAOAAKR1C3AKR1C2AKR1C1
SCHEMBL21089389 0.82 TOP2A (0.63) ALOX5MAOAAKR1C3AKR1C2AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328205-B2 Iron(III) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-05-03 US disclosed
US-9328205-B2 Iron(III) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-05-03 US disclosed
US-20140371056-A1 Iron(III) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW COMING CORPORATION (US) 2014-12-18 US disclosed
US-20140371056-A1 Iron(III) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW COMING CORPORATION (US) 2014-12-18 US disclosed
WO-2013052585-A2 IRON(III) CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-04-11 WO disclosed
US-20050020684-A1 Modulators of peroxisome proliferator activated receptors ELI LILLY AND COMPANY 2005-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050020684-A1 Modulators of peroxisome proliferator activated receptors NCOA4, PPARG, PPARA ALOX5 1617/4885MAOA 3441/4885AKR1C3 389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.