SCHEMBL678436

SCHEMBL678436

Cc1ccc(NC(=N)Nc2ccc(C)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.56
POLB P06746 1/20 0.54
RAB9A P51151 5/20 0.52
NPC1 O15118 4/20 0.52
MAPT P10636 2/20 0.52
KIF11 P52732 1/20 0.48
MEN1 O00255 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C19 P33261 1/20 0.48
HTT P42858 1/20 0.48
KMT2A Q03164 1/20 0.48
TGM2 P21980 1/20 0.48
KDM4E B2RXH2 1/20 0.48
HPGD P15428 1/20 0.47
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
GRIN1 Q05586 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIN2B Q13224 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL636496 0.91 HPGD (0.58) TDP1POLBRAB9ANPC1MAPT
SCHEMBL3056662 0.90 TDP1 (0.52) TDP1POLBRAB9ANPC1MAPT
SCHEMBL12513997 0.88 POLB (0.50) TDP1POLBRAB9ANPC1MAPT
SCHEMBL12253600 0.83 POLB (0.46) TDP1POLBRAB9ANPC1MAPT
SCHEMBL650677 0.83 KIF11 (0.48) TDP1POLBRAB9ANPC1MAPT
SCHEMBL12035256 0.82 TDP1 (0.60) TDP1POLBRAB9ANPC1MAPT
SCHEMBL20315921 0.81 MEN1 (0.61) TDP1POLBRAB9ANPC1MAPT
Hydrochloric Acid SCHEMBL11844402 0.81 KIF11 (0.47) TDP1POLBRAB9ANPC1MAPT
Hydrochloric Acid SCHEMBL21530444 0.81 KIF11 (0.47) TDP1POLBRAB9ANPC1MAPT
SCHEMBL20315922 0.81 RAB9A (0.49) TDP1RAB9ANPC1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3683005-B1 FLUX AND SOLDER PASTE SENJU METAL INDUSTRY CO (JP) 2022-01-26 EP claimed
EP-2611518-B1 REGENERABLE IONIC LIQUID SOLVENTS FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2016-08-24 EP claimed
EP-1353986-B1 COLORED THERMOPLASTIC RESIN COMPOSITIONS FOR LASER WELDING, ANTHRAQUINONE COLORANTS THEREFOR AND MOLDED PRODUCT THEREFROM DU PONT (US) 2006-04-12 EP claimed
EP-1334148-B1 COLORED THERMOPLASTIC RESIN COMPOSITIONS FOR LASER WELDING, COLORANTS THEREFOR OF MIXTURES OF AMINE SALTS OF ANTHRAQUINONE AND MONOAZO COMPLEX DYES, AND MOLDED PRODUCT THEREFROM DU PONT (US) 2006-03-15 EP claimed
US-20050282960-A1 Epoxy ebonite compositions 3L&T, INC. 2005-12-22 US claimed
US-20040143037-A1 Epoxy ebonite compositions 3L&T, INC. (US) 2004-07-22 US claimed
EP-0461252-B1 THERMOPLASTIC ELASTOMERS BASED UPON CHLORINATED OR CHLOROSULFONATED POLYETHYLENE AND A CRYSTALLINE OLEFIN POLYMER DOW CHEMICAL CO (US) 1998-06-03 EP claimed
JP-2703113-B2 1998-01-26 JP claimed
EP-0336735-B1 Thermoplastic elastomers based upon chlorinated polyethylene and a crystalline polypropylene DOW CHEMICAL CO (US) 1994-12-07 EP claimed
US-5286795-A Plasticizing; vulcanization with a 2,5-dimercapto-1,3,4-thiadiazole; dispersion in unvulcanized polymer; blend of themoplastic and thermosetting resins THE DOW CHEMICAL COMPANY (US) 1994-02-15 US claimed
EP-0461252-A4 THERMOPLASTIC ELASTOMERS BASED UPON CHLORINATED OR CHLOROSULFONATED POLYETHYLENE AND A CRYSTALLINE OLEFIN POLYMER 1992-05-06 EP claimed
EP-0461252-A1 THERMOPLASTIC ELASTOMERS BASED UPON CHLORINATED OR CHLOROSULFONATED POLYETHYLENE AND A CRYSTALLINE OLEFIN POLYMER THE DOW CHEMICAL COMPANY (US) 1991-12-18 EP claimed
WO-1991009903-A1 THERMOPLASTIC ELASTOMERS BASED UPON CHLORINATED OR CHLOROSULFONATED POLYETHYLENE AND A CRYSTALLINE OLEFIN POLYMER THE DOW CHEMICAL COMPANY (US) 1991-07-11 WO claimed
US-4978703-A THIADIAZOLE VULCANIZERS THE DOW CHEMICAL COMPANY (US) 1990-12-18 US claimed
US-4978716-A BLENDING WITH A PLASTISIZER AND BASE; VULCANIZATION WITH A 2,5-DIMERCAPTO-1,3,4-THIADIAZOLE THE DOW CHEMICAL COMPANY (US) 1990-12-18 US claimed
US-4910245-A Containing a plasticizer and a vulcanizing agent THE DOW CHEMICAL COMPANY (US) 1990-03-20 US claimed
EP-0336735-A2 Thermoplastic elastomers based upon chlorinated polyethylene and a crystalline polypropylene THE DOW CHEMICAL COMPANY (US) 1989-10-11 EP claimed
US-4486356-A BY-PRODUCT INHIBITION GESHURI LABORATORIES, LTD. (IL) 1984-12-04 US claimed
EP-0098034-A2 A process for producing n-phosphonomethylglycine derivatives and herbicidal compounds and compositions prepared thereby Geshuri Laboratories Ltd. (IL) 1984-01-11 EP claimed
US-4288576-A BASIC MATERIAL HERCULES INCORPORATED (US) 1981-09-08 US claimed