Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.44 |
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | HTR6 | P50406 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CALML3 | P27482 | 1/20 | 0.33 |
| ▸ | SDHA | P31040 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506847 | 1.00 | MAOA (0.44) | MAOAF10MAOBHTR6LMNA | |
| SCHEMBL3029206 | 0.87 | MAOA (0.47) | MAOAF10MAOBHTR6METAP2 | |
| SCHEMBL6686796 | 0.87 | MAOA (0.47) | MAOAF10MAOBHTR6METAP2 | |
| SCHEMBL3829481 | 0.84 | MAOA (0.49) | MAOAF10MAOBHTR6LMNA | |
| SCHEMBL14433150 | 0.83 | MAOA (0.44) | MAOAF10MAOBHTR6LMNA | |
| SCHEMBL5998601 | 0.81 | MAOA (0.51) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL6505153 | 0.80 | MAOA (0.58) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL6505152 | 0.80 | MAOA (0.58) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL3829530 | 0.80 | MAOA (0.47) | MAOAF10MAOBHTR6LMNA | |
| SCHEMBL3831636 | 0.80 | MAOA (0.47) | MAOAF10MAOBHTR6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005087763-A9 | DIPHENYLMETHYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE INC (US) | 2005-10-27 | — | — | WO | disclosed |
| WO-2005082897-A1 | OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |