Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3029206 | 1.00 | MAOA (0.47) | MAOACYP11B2F10METAP2CYP11B1 | |
| SCHEMBL5998601 | 0.89 | MAOA (0.51) | MAOAF10TRIM24MAOB | |
| SCHEMBL3039865 | 0.88 | F10 (0.40) | MAOACYP11B2F10METAP2CYP11B1 | |
| SCHEMBL3043798 | 0.88 | F10 (0.40) | MAOACYP11B2F10METAP2CYP11B1 | |
| SCHEMBL3829481 | 0.87 | MAOA (0.49) | MAOAF10MAOBHTR6 | |
| SCHEMBL14433150 | 0.87 | MAOA (0.44) | MAOAF10MAOBHTR6 | |
| SCHEMBL6506847 | 0.87 | MAOA (0.44) | MAOAF10METAP2MAOBHTR6 | |
| SCHEMBL6506845 | 0.87 | MAOA (0.44) | MAOAF10METAP2MAOBHTR6 | |
| SCHEMBL3829530 | 0.84 | MAOA (0.47) | MAOAF10MAOBHTR6 | |
| SCHEMBL3831636 | 0.84 | MAOA (0.47) | MAOAF10MAOBHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478629-A1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN COMPANY (US) | 2004-11-24 | — | — | EP | claimed |
| WO-2003072553-A1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN COMPANY (US) | 2003-09-04 | — | — | WO | claimed |