Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | WDR5 | P61964 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ENGASE | Q8NFI3 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5762670 | 0.92 | MAPT (0.36) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL5762509 | 0.91 | MAPT (0.38) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL5763137 | 0.91 | MAPT (0.38) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL5760947 | 0.90 | GAA (0.35) | MAPTNPC1RAB9ACYP2C9NOD1 | |
| SCHEMBL5761996 | 0.87 | MAPT (0.44) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL5763367 | 0.87 | MAPT (0.44) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL5762005 | 0.87 | MAPT (0.43) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL5762524 | 0.87 | MAPT (0.39) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL5760766 | 0.86 | MAPT (0.39) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL5762958 | 0.86 | MAPT (0.37) | MAPTNPC1RAB9ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143423-A1 | Prodrugs of proton pump inhibitors background of the invention | GARST MICHAEL (US) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143423-A1 | Prodrugs of proton pump inhibitors background of the invention | ABCB11, SLC10A2, SI | MAPT 4128/4885NPC1 374/4885RAB9A 555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.