Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224666 | 0.84 | PDE7A (0.60) | ALDH1A1TSHRPDE7ASMN1; SMN2MAPT | |
| SCHEMBL34723 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TSHRSMN1; SMN2HPGDMEN1 | |
| SCHEMBL11027382 | 0.76 | PDE7A (0.56) | ALDH1A1TSHRPDE7ASMN1; SMN2MAPT | |
| SCHEMBL11209984 | 0.76 | PDE7A (0.56) | ALDH1A1TSHRPDE7ASMN1; SMN2MAPT | |
| SCHEMBL8734150 | 0.75 | PDE7A (0.51) | ALDH1A1PDE7ASMN1; SMN2MAPTPKM | |
| SCHEMBL18614898 | 0.75 | PDE7A (0.51) | ALDH1A1TSHRPDE7ASMN1; SMN2MAPT | |
| SCHEMBL11319431 | 0.74 | PDE7A (0.55) | ALDH1A1TSHRPDE7ASMN1; SMN2MAPT | |
| SCHEMBL2942164 | 0.74 | KMT2A (0.44) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL83607 | 0.73 | PDE7A (0.53) | ALDH1A1PDE7ASMN1; SMN2MAPTPKM | |
| SCHEMBL14113991 | 0.72 | ALDH1A1 (0.50) | ALDH1A1TSHRPDE7ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049582-A1 | METHOD OF PREPARATION OF NOVEL NUCLEOSIDE ANALOGS AND USES | AUSPEX PHARMACEUTICALS, INC. (US) | 2005-06-02 | — | — | WO | disclosed |