Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224666 | 0.87 | PDE7A (0.60) | PDE7ASMN1; SMN2HSD17B10SLC6A2SLC6A4 | |
| SCHEMBL3384869 | 0.85 | PDE7A (0.58) | PDE7ASMN1; SMN2HSD17B10SLC6A2SLC6A4 | |
| SCHEMBL11209984 | 0.83 | PDE7A (0.56) | PDE7ASMN1; SMN2HSD17B10SLC6A2SLC6A4 | |
| SCHEMBL11027382 | 0.83 | PDE7A (0.56) | PDE7ASMN1; SMN2HSD17B10SLC6A2SLC6A4 | |
| SCHEMBL11319431 | 0.82 | PDE7A (0.55) | PDE7ASMN1; SMN2HSD17B10SLC6A2SLC6A4 | |
| SCHEMBL14113991 | 0.79 | ALDH1A1 (0.50) | PDE7ASMN1; SMN2HSD17B10SLC6A2SLC6A4 | |
| SCHEMBL4910926 | 0.79 | PDE7A (0.49) | PDE7ASMN1; SMN2HSD17B10SLC6A2SLC6A4 | |
| SCHEMBL31272173 | 0.79 | PDE7A (0.78) | PDE7ASMN1; SMN2HSD17B10SLC6A2SLC6A4 | |
| SCHEMBL875772 | 0.79 | PDE7A (0.78) | PDE7ASMN1; SMN2HSD17B10SLC6A2SLC6A4 | |
| SCHEMBL8734150 | 0.78 | PDE7A (0.51) | PDE7ASMN1; SMN2HSD17B10SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9527846-B2 | Kinase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-12-27 | — | — | US | disclosed |
| US-9480753-B2 | FGF21 derivatives with albumin binder A-B-C-D-E- and their use | NOVO NORDISK A/S (DK) | 2016-11-01 | — | — | US | disclosed |
| US-9480753-B2 | FGF21 derivatives with albumin binder A-B-C-D-E- and their use | NOVO NORDISK A/S (DK) | 2016-11-01 | — | — | US | disclosed |
| US-9440974-B2 | Kinase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-09-13 | — | — | US | disclosed |
| US-20160229852-A1 | KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-08-11 | — | — | US | disclosed |
| US-9359354-B2 | Kinase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-06-07 | — | — | US | disclosed |
| US-9315503-B2 | Kinase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-04-19 | — | — | US | disclosed |
| US-20160016953-A1 | KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A (IT) | 2016-01-21 | — | — | US | disclosed |
| US-20150344475-A1 | KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-12-03 | — | — | US | disclosed |
| US-20150327547-A1 | N-ALKYLTHIO BETA-LACTAMS, ALKYL-COENZYME A ASYMMETRIC DISULFIDES, AND ARYL-ALKYL DISULFIDES AS ANTI-BACTERIAL AGENTS | UNIVERSITY OF SOUTH FLORIDA (US) | 2015-11-19 | — | — | US | disclosed |
| US-8129505-B2 | Formed by catalytic polymerization; antibody conjugates | UCB PHARMA S.A. (BE) | 2012-03-06 | — | — | US | disclosed |
| US-8129505-B2 | Formed by catalytic polymerization; antibody conjugates | UCB PHARMA S.A. (BE) | 2012-03-06 | — | — | US | disclosed |
| EP-1926757-B1 | ANTIBODY-COMB POLYMER CONJUGATE | UCB PHARMA SA (BE) | 2012-02-22 | — | — | EP | disclosed |
| US-20100216715-A1 | FGF21 Derivatives With Albumin Binder A-B-C-D-E- And Their Use | NOVO NORDISK A/S (DK) | 2010-08-26 | — | — | US | disclosed |
| US-20100021480-A1 | BIOACTIVE SUBSTANCE-BLOOD PROTEIN CONJUGATE AND STABILIZATION OF A BIOACTIVE SUBSTANCE USING THE SAME | PEPTRON CO., LTD (KR) | 2010-01-28 | — | — | US | disclosed |
| US-20080220005-A1 | Comb Polymers | UCB PHARMA S.A. (BE) | 2008-09-11 | — | — | US | disclosed |
| US-20080220005-A1 | Comb Polymers | UCB PHARMA S.A. (BE) | 2008-09-11 | — | — | US | disclosed |
| US-20080182815-A1 | Act against several infective agents, and most notably Bacillus spp. and Staphylococcus spp., including infection caused by methicillin-resistant Staphylococcus aureus (MRSA) | UNIVERSITY OF SOUTH FLORIDA | 2008-07-31 | — | — | US | disclosed |
| US-20080182815-A1 | Act against several infective agents, and most notably Bacillus spp. and Staphylococcus spp., including infection caused by methicillin-resistant Staphylococcus aureus (MRSA) | UNIVERSITY OF SOUTH FLORIDA | 2008-07-31 | — | — | US | disclosed |
| WO-2007031734-A1 | COMB POLYMERS | UCB PHARMA S.A. (BE) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182815-A1 | Act against several infective agents, and most notably Bacillus spp. and Staphylococcus spp., including infection caused by methicillin-resistant Staphylococcus aureus (MRSA) | SQOR, TST, COASY | PDE7A 3283/4885SMN1; SMN2 1758/4885HSD17B10 156/4885 |
| US-20160016953-A1 | KINASE INHIBITORS | MAP3K1, MAP3K2, MAP3K6 | PDE7A 1195/4885SMN1; SMN2 3494/4885HSD17B10 1721/4885 |
| US-20100216715-A1 | FGF21 Derivatives With Albumin Binder A-B-C-D-E- And Their Use | FABP1, FABP4, FGFR1 | PDE7A 3098/4885SMN1; SMN2 3742/4885HSD17B10 137/4885 |
| US-20150344475-A1 | KINASE INHIBITORS | MAPK1, MAP3K1, MAPK6 | PDE7A 1373/4885SMN1; SMN2 3148/4885HSD17B10 3402/4885 |
| US-20100021480-A1 | BIOACTIVE SUBSTANCE-BLOOD PROTEIN CONJUGATE AND STABILIZATION OF A BIOACTIVE SUBSTANCE USING THE SAME | SERPINA6, CSTB, PLG | PDE7A 992/4885SMN1; SMN2 1093/4885HSD17B10 3063/4885 |
| US-20150327547-A1 | N-ALKYLTHIO BETA-LACTAMS, ALKYL-COENZYME A ASYMMETRIC DISULFIDES, AND ARYL-ALKYL DISULFIDES AS ANTI-BACTERIAL AGENTS | COASY, SQOR, TST | PDE7A 1520/4885SMN1; SMN2 2837/4885HSD17B10 160/4885 |
| US-20160229852-A1 | KINASE INHIBITORS | MAPK1, MAP3K1, MAPK6 | PDE7A 1373/4885SMN1; SMN2 3148/4885HSD17B10 3402/4885 |
| US-20080220005-A1 | Comb Polymers | C9, F13B, PYM1 | PDE7A 4792/4885SMN1; SMN2 3037/4885HSD17B10 3706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.