Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507034 | 0.70 | HPGD (0.40) | LMNANPC1HSD17B10ABL1ALDH1A1 | |
| SCHEMBL10524336 | 0.64 | CA2 (0.43) | LMNASMN1; SMN2CA1CA2CA4 | |
| SCHEMBL6501402 | 0.64 | PIK3CB (0.39) | PIK3CBLMNAPIK3CANPC1PIK3CD | |
| SCHEMBL5153254 | 0.62 | — | — | |
| SCHEMBL1208218 | 0.61 | DDX3X (0.54) | LMNANPC1HSD17B10ALDH1A1POLB | |
| SCHEMBL4866067 | 0.61 | NPC1 (0.65) | LMNANPC1HSD17B10ALDH1A1MAPT | |
| SCHEMBL1540449 | 0.61 | ALDH1A1 (0.49) | LMNANPC1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL5154436 | 0.61 | — | — | |
| SCHEMBL10957760 | 0.60 | GLP1R (0.38) | PIK3CBLMNAPIK3CAPIK3CDPIK3CG | |
| SCHEMBL15884552 | 0.60 | ALDH1A1 (0.53) | LMNANPC1HSD17B10ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014591-A1 | 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2005-02-17 | — | — | WO | claimed |