Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491444 | 0.84 | HTR1A (0.42) | HTR1AHTR7TSHRSMN1; SMN2KMT2A | |
| SCHEMBL6508045 | 0.84 | HTR1A (0.42) | HTR1AHTR7TSHRSMN1; SMN2KMT2A | |
| SCHEMBL11142307 | 0.76 | ADRB2 (0.51) | — | |
| SCHEMBL11477551 | 0.75 | ALOX15 (0.49) | TSHRALOX15NR2E1SMN1; SMN2KMT2A | |
| SCHEMBL15360076 | 0.73 | LNPEP (0.33) | HTR1AHTR7LNPEP | |
| SCHEMBL2110330 | 0.73 | KDM4E (0.38) | HTR1AHTR7TSHRSMN1; SMN2KMT2A | |
| SCHEMBL14300695 | 0.73 | KDM4E (0.36) | HTR1AHTR7KMT2AGRIN1GRIN2B | |
| SCHEMBL6074662 | 0.72 | CHRNB2 (0.46) | TSHRALOX15NR2E1SMN1; SMN2KMT2A | |
| SCHEMBL27580967 | 0.72 | CHRNB2 (0.46) | TSHRALOX15NR2E1SMN1; SMN2KMT2A | |
| SCHEMBL11246142 | 0.72 | ACHE (0.45) | HTR1AHTR7SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4115575-A | CARDIOVASCULAR DISORDERS | CIBA-GEIGY CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |