Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.45 |
| ▸ | PPARG | P37231 | 9/20 | 0.42 |
| ▸ | PPARD | Q03181 | 9/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508221 | 0.80 | PPARA (0.61) | PPARAPPARGPPARD | |
| SCHEMBL6505767 | 0.75 | PPARA (0.48) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL3943367 | 0.71 | PPARA (0.64) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL3944237 | 0.71 | PPARA (0.63) | PPARAPPARGPPARD | |
| SCHEMBL3945778 | 0.70 | PPARA (0.64) | PPARAPPARGPPARD | |
| SCHEMBL6498726 | 0.69 | PPARA (0.46) | PPARAPPARGPPARD | |
| SCHEMBL28622516 | 0.66 | ALOX15 (0.60) | PPARAPPARGPPARD | |
| SCHEMBL4450745 | 0.65 | PPARA (0.51) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL4450866 | 0.65 | PPARA (0.58) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL15709546 | 0.65 | PPARG (0.48) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |