Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.58 |
| ▸ | PPARG | P37231 | 7/20 | 0.58 |
| ▸ | PPARD | Q03181 | 8/20 | 0.57 |
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.53 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.53 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.53 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.53 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.53 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16973511 | 0.87 | LDHA (0.49) | PPARAPPARGPPARDLDHA | |
| SCHEMBL28622516 | 0.84 | ALOX15 (0.60) | PPARAPPARGPPARDLDHA | |
| SCHEMBL8000384 | 0.81 | PDCD1 (0.56) | PPARGLDHA | |
| SCHEMBL6339536 | 0.81 | PDCD1 (0.56) | PPARGLDHA | |
| SCHEMBL1682680 | 0.81 | FOS (0.60) | PPARAPPARGPPARDLDHA | |
| SCHEMBL15760890 | 0.81 | PDCD1 (0.56) | PPARGLDHA | |
| SCHEMBL1819058 | 0.79 | LDHA (0.52) | LDHA | |
| SCHEMBL28611663 | 0.78 | PPARA (0.64) | PPARAPPARGPPARDLDHA | |
| SCHEMBL5797127 | 0.77 | ALDH1A1 (0.53) | LDHA | |
| SCHEMBL4459430 | 0.77 | PPARA (0.69) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482484-B2 | Carboxylic acids and derivatives for the treatment of and preventing diabetes and dyslipidaemia | MERCK PATENT GMBH (DE) | 2009-01-27 | — | — | US | disclosed |