SCHEMBL6508447

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6498382	0.89	ITK (0.45)	ITKSCN9APARP1IRAK4LMNA
	SCHEMBL6467910	0.89	ITK (0.44)	ITKSCN9APARP1IRAK4LMNA
	SCHEMBL6468754	0.88	ITK (0.43)	ITKSCN9APARP1IRAK4LMNA
	SCHEMBL6507603	0.87	ITK (0.49)	ITKSCN9APARP1IRAK4LMNA
	SCHEMBL6498196	0.85	ITK (0.42)	ITKSCN9APARP1IRAK4LMNA
	SCHEMBL6499548	0.84	ITK (0.45)	ITKSCN9AIRAK4LMNASMN1; SMN2
	SCHEMBL6501255	0.84	ITK (0.45)	ITKSCN9AIRAK4LMNASMN1; SMN2
	SCHEMBL6470279	0.84	SCN9A (0.42)	ITKSCN9APARP1IRAK4LMNA
	SCHEMBL6504845	0.83	ITK (0.46)	ITKSCN9AIRAK4LMNASMN1; SMN2
	SCHEMBL6500001	0.83	ITK (0.50)	ITKSCN9APARP1IRAK4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.