SCHEMBL65085

SCHEMBL65085

Nc1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18783134 0.97 DPYD (0.50)
Hydrochloric Acid SCHEMBL29256236 0.97 DPYD (0.50)
SCHEMBL23211189 0.97 DPYD (0.50)
Potassium SCHEMBL29524710 0.97 DPYD (0.50)
Propene SCHEMBL29002281 0.87 DPYD (0.52)
SCHEMBL3321070 0.75
SCHEMBL5801644 0.72 ALDH1A1 (0.64)
SCHEMBL6573722 0.70
SCHEMBL29396848 0.69 DPYD (0.42)
SCHEMBL2037916 0.69 DPYD (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2220 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116438164-B Method for preparing 3, 6-diaminopyrazine-2, 5-dicarboxylic acid and synthetic intermediate thereof HANGZHOU ZHONGMEI HUADONG PHARMACEUTICAL Co.,Ltd. (CN) 2026-05-26 CN claimed
EP-4560315-A2 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2025-05-28 EP claimed
CN-114555087-B Anodic oxidation of 5-aminouracil 麦迪贝肯有限公司 2025-04-18 CN claimed
CN-119752427-A Low-permeability oil reservoir plugging agent with biomimetic mineralization effect and preparation method thereof 中石化石油工程技术服务股份有限公司 2025-04-04 CN claimed
EP-3980554-B1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES HOFFMANN LA ROCHE (CH) 2025-03-26 EP claimed
CN-118028794-A Cyanide-free chemical reduction gold plating solution and gold plating method 深圳创智芯联科技股份有限公司 2024-05-14 CN claimed
US-20240025864-A1 METHOD FOR PREPARING 3,6-DIAMINOPYRAZINE-2,5-DICARBOXYLIC ACID AND SYNTHETIC INTERMEDIATE THEREOF HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO., LTD. (CN) 2024-01-25 US claimed
CN-111333840-B Intrinsic self-repairing amino acid polymer and preparation method thereof 安徽东凯生物科技股份有限公司 2023-10-27 CN claimed
CN-111570216-B Composite protective film layer with silane transition layer, preparation method thereof and product 江苏菲沃泰纳米科技股份有限公司 2023-10-13 CN claimed
CN-116874434-A Preparation method of medicinal compound 齐泽(云南)生物科技有限公司 2023-10-13 CN claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
EP-0726274-A2 G-cap stabilized oligonucleotides HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-14 EP claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0701446-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1996-03-20 EP claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
WO-1994027627-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1994-12-08 WO claimed
US-5252449-A Rhodium salt, sensitized with black and white developer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-10-12 US claimed
US-5118800-A Oligonucleotides possessing a primary amino group in the terminal nucleotide CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-06-02 US claimed
EP-0484660-A1 Novel 5-(Phenoxyalcanoylamino)-uraciles, methodes for preparing them and their use as medicaments ARZNEIMITTELWERK DRESDEN GmbH (DE) 1992-05-13 EP claimed