Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.47 |
| ▸ | CNR2 | P34972 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509465 | 0.81 | GABRA2 (0.44) | CNR1CNR2 | |
| SCHEMBL1689143 | 0.69 | CNR1 (0.47) | CNR1CNR2KCNH2OPRL1KDM4E | |
| SCHEMBL11610988 | 0.68 | TDP1 (0.47) | CYP3A4CYP2C19 | |
| SCHEMBL4788342 | 0.67 | CRHR1 (0.46) | CNR1CNR2CRHR1KDM4EALDH1A1 | |
| SCHEMBL4563433 | 0.67 | KMT2A (0.50) | CNR1CNR2KCNH2OPRL1 | |
| SCHEMBL1689384 | 0.67 | GRM1 (0.47) | CNR1CNR2KCNH2KDM4E | |
| SCHEMBL1753298 | 0.67 | F2RL3 (0.46) | CNR1CNR2KCNH2 | |
| SCHEMBL1753186 | 0.66 | KMT2A (0.46) | CNR1CNR2KCNH2 | |
| SCHEMBL1753407 | 0.66 | CNR1 (0.44) | CNR1CNR2KCNH2 | |
| SCHEMBL1688949 | 0.65 | CNR1 (0.48) | CNR1CNR2KCNH2OPRL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061504-A1 | BICYCLIC PYRIDAZINONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | claimed |
| WO-2005061504-A1 | BICYCLIC PYRIDAZINONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005061504-A1 | BICYCLIC PYRIDAZINONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |