Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 10/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508555 | 0.81 | CNR1 (0.47) | CNR2CNR1 | |
| SCHEMBL6511635 | 0.77 | BRD4 (0.44) | CNR1 | |
| SCHEMBL6532623 | 0.70 | NPC1 (0.47) | CNR1MEN1KMT2A | |
| SCHEMBL11610988 | 0.69 | TDP1 (0.47) | KMT2A | |
| SCHEMBL4503440 | 0.67 | GABRA2 (0.64) | GABRA2GABRB2CNR2CNR1MEN1 | |
| SCHEMBL6532620 | 0.67 | CNR1 (0.47) | CNR2CNR1 | |
| SCHEMBL4513537 | 0.66 | CNR2 (0.65) | GABRA2GABRB2CNR2CNR1 | |
| SCHEMBL4500829 | 0.66 | CNR2 (0.65) | GABRA2GABRB2CNR2CNR1 | |
| SCHEMBL1753154 | 0.65 | TP53 (0.69) | KMT2A | |
| SCHEMBL21733154 | 0.65 | KMO (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061504-A1 | BICYCLIC PYRIDAZINONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | claimed |
| WO-2005061504-A1 | BICYCLIC PYRIDAZINONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |