Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | PPM1D | O15297 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6515075 | 0.89 | GAA (0.41) | NPC1FAAHALDH1A1GAAL3MBTL1 | |
| SCHEMBL6533750 | 0.89 | GAA (0.43) | NPC1FAAHALDH1A1GAAL3MBTL1 | |
| SCHEMBL6511522 | 0.88 | GAA (0.40) | NPC1FAAHALDH1A1GAAL3MBTL1 | |
| SCHEMBL6509181 | 0.83 | ALDH1A1 (0.39) | NPC1ALDH1A1GAAL3MBTL1HTT | |
| SCHEMBL6509243 | 0.83 | SLC2A1 (0.48) | NPC1ALDH1A1 | |
| SCHEMBL6511195 | 0.81 | NPC1 (0.42) | NPC1ALDH1A1L3MBTL1NR1H4SLC6A2 | |
| SCHEMBL6508828 | 0.81 | MAPT (0.43) | NPC1 | |
| SCHEMBL6516272 | 0.80 | ATM (0.41) | NPC1ALDH1A1L3MBTL1NR1H4SLC6A2 | |
| SCHEMBL6512357 | 0.79 | TAS2R14 (0.43) | NPC1ALDH1A1L3MBTL1HTTRAB9A | |
| SCHEMBL2702398 | 0.78 | NPC1 (0.56) | NPC1FAAHALDH1A1MCOLN3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |