Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | DHFR | P00374 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15456750 | 0.85 | CYP3A4 (0.82) | RAB9AKDM4EMAPTMEN1KMT2A | |
| SCHEMBL1627936 | 0.85 | CYP3A4 (0.82) | RAB9AKDM4EMAPTMEN1KMT2A | |
| SCHEMBL27940000 | 0.82 | ADORA3 (0.74) | RAB9AKDM4EMAPTMEN1KMT2A | |
| SCHEMBL27940011 | 0.82 | KDM4E (0.60) | RAB9AKDM4EMAPTMEN1KMT2A | |
| SCHEMBL27405000 | 0.82 | CYP3A4 (0.79) | RAB9AKDM4EMAPTMEN1KMT2A | |
| SCHEMBL622846 | 0.81 | DDR2 (1.00) | DDR2RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL7162949 | 0.79 | KDM4E (0.74) | RAB9AKDM4EMAPTMEN1KMT2A | |
| SCHEMBL5130608 | 0.77 | MAPT (0.70) | DDR2RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL29167450 | 0.76 | KDM4E (0.56) | RAB9AKDM4EMAPTMEN1KMT2A | |
| SCHEMBL3537369 | 0.76 | RAB9A (0.78) | RAB9AKDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005107760-A1 | COMPOUNDS AND COMPOSITIONS AS INDUCERS OF KERATINOCYTE DIFFERENTIATION | IRM LLC (BM) | 2005-11-17 | — | — | WO | disclosed |