Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5989876 | 0.81 | ADRB2 (0.42) | PARP1ADRB2HTTDHODHALDH1A1 | |
| SCHEMBL8265189 | 0.81 | HRH4 (0.46) | PARP1ADRB2HTTDHODHALDH1A1 | |
| SCHEMBL6142607 | 0.81 | RPS6KA3 (0.60) | PARP1RPS6KA3ADRB2HTTDHODH | |
| SCHEMBL6506668 | 0.78 | ADRB2 (0.55) | PARP1ADRB2HTTDHODHALDH1A1 | |
| SCHEMBL6507007 | 0.78 | ALDH1A1 (0.57) | PARP1RPS6KA3ADRB2HTTDHODH | |
| SCHEMBL24463162 | 0.78 | ADRB2 (0.41) | PARP1ADRB2HTTDHODHALDH1A1 | |
| SCHEMBL6510341 | 0.78 | PARP1 (0.42) | PARP1RPS6KA3ADRB2HTTDHODH | |
| SCHEMBL7032565 | 0.78 | PARP1 (0.42) | PARP1RPS6KA3ADRB2HTTALDH1A1 | |
| SCHEMBL19329481 | 0.77 | DDAH1 (0.42) | RPS6KA3HTTALDH1A1GAAMAPT | |
| SCHEMBL13594653 | 0.77 | ADRB2 (0.52) | PARP1ADRB2HTTDHODHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017153952-A1 | 5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-09-14 | — | — | WO | disclosed |
| WO-2005108374-A1 | INSECTICIDAL DIAZOLE AND TRIAZOLE DERIVATIVES | FMC CORPORATION (US) | 2005-11-17 | — | — | WO | disclosed |