SCHEMBL650918

SCHEMBL650918

CCN(CC)CCc1ccccc1O

nearest known ligand 0.76

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 3/20 0.76
HTR6 P50406 1/20 0.53
TAAR1 Q96RJ0 1/20 0.50
HTR2A P28223 3/20 0.47
HSPA5 P11021 1/20 0.46
TSHR P16473 2/20 0.46
MPO P05164 1/20 0.44
HTR1D P28221 1/20 0.44
PRKCI P41743 1/20 0.43
CHEK1 O14757 1/20 0.42
PIM1 P11309 1/20 0.42
IDO1 P14902 1/20 0.42
LTK P29376 1/20 0.42
LIMK1 P53667 1/20 0.42
CLK4 Q9HAZ1 1/20 0.42
CYP2D6 P10635 1/20 0.42
HIF1A Q16665 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5983439 0.87 HTR1A (0.59) HTR1ATAAR1TSHRMPO
SCHEMBL28766915 0.86 HTR1A (1.00) HTR1ATAAR1HTR2ATSHRCYP2D6
SCHEMBL10490573 0.83 HTR1A (0.55) HTR1AHTR6HTR2ATSHRHTR1D
SCHEMBL28794561 0.82 HTR2A (0.68) HTR1ATAAR1HTR2AHSPA5TSHR
SCHEMBL13051280 0.82 TSHR (0.58) HTR1AHSPA5TSHRPRKCICHEK1
SCHEMBL10964245 0.80 HTR1A (0.75) HTR1ATAAR1TSHR
SCHEMBL9777892 0.80 HTR1A (0.75) HTR1ATAAR1TSHR
SCHEMBL20175942 0.80 TSHR (0.59) HTR1AHSPA5TSHRPRKCICYP2D6
SCHEMBL10962774 0.80 HTR1A (0.70) HTR1ATAAR1HTR2AHSPA5TSHR
SCHEMBL36797 0.79 HTR2A (0.65) HTR1AHTR6TAAR1HTR2AHSPA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11931711-B2 Microcapsule clusters ENCAPSYS, LLC (US) 2024-03-19 US disclosed
US-20230264161-A1 Microcapsule Clusters ENCAPSYS LLC (US) 2023-08-24 US disclosed
EP-3946710-A1 MICROCAPSULE CLUSTERS Encapsys, LLC (US) 2022-02-09 EP disclosed
EP-3206782-B1 CONTROLLED RELEASE DUAL WALLED MICROCAPSULES PROCTER & GAMBLE (US) 2021-12-15 EP disclosed
US-11180714-B2 Controlled release microcapsules ENCAPSYS, LLC (US) 2021-11-23 US disclosed
US-20200316551-A1 Microcapsule Clusters ENCAPSYS, LLC 2020-10-08 US disclosed
US-20190345410-A1 CONTROLLED RELEASE MICROCAPSULES ENCAPSYS, LLC (US) 2019-11-14 US disclosed
US-10456766-B2 Controlled release dual walled microcapsules ENCAPSYS LLC (US) 2019-10-29 US disclosed
US-10428294-B2 Controlled release microcapsules ENCAPSYS, LLC (US) 2019-10-01 US disclosed
US-20190282989-A1 CONTROLLED RELEASE DUAL WALLED MICROCAPSULES ENCAPSYS LLC (US) 2019-09-19 US disclosed
US-4699931-A REACTING POLYISOCYANATE WITH POLYEPOXIDE-THERMAL STABILITY OLIN CORPORATION (US) 1987-10-13 US disclosed
EP-0028331-B2 Process for preparing urethanes BAYER AG (DE) 1987-05-20 EP disclosed
EP-0027940-B2 PROCESS FOR PREPARING URETHANES BAYER AG (DE) 1986-12-30 EP disclosed
EP-0087047-B1 PROCESS FOR THE PREPARATION OF N SUBSTITUTED URETHANES BAYER AG (DE) 1985-08-07 EP disclosed
EP-0027940-B1 PROCESS FOR PREPARING URETHANES BAYER AG (DE) 1983-09-14 EP disclosed
EP-0087047-A2 Process for the preparation of N substituted urethanes BAYER AG (DE) 1983-08-31 EP disclosed
US-4388238-A FROM PRIMARY AMINES, ALCOHOLS, AND CARBONYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1983-06-14 US disclosed
EP-0028331-B1 Process for preparing urethanes BAYER AG (DE) 1982-12-15 EP disclosed
US-4126742-A High-modulus polyisocyanurate elastomers THE UPJOHN COMPANY (US) 1978-11-21 US disclosed
US-4126741-A High-modulus polyisocyanurate elastomers THE UPJOHN COMPANY (US) 1978-11-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190345410-A1 CONTROLLED RELEASE MICROCAPSULES NSF, CRH, CHMP4B HTR1A 817/4885HTR6 281/4885TAAR1 1848/4885
US-10456766-B2 Controlled release dual walled microcapsules MYADM, MCHR2, MCHR1 HTR1A 117/4885HTR6 83/4885TAAR1 148/4885
US-10428294-B2 Controlled release microcapsules NSF, CRH, CHMP4B HTR1A 817/4885HTR6 281/4885TAAR1 1848/4885
US-20190282989-A1 CONTROLLED RELEASE DUAL WALLED MICROCAPSULES MYADM, MCHR2, MCHR1 HTR1A 117/4885HTR6 83/4885TAAR1 148/4885
US-11180714-B2 Controlled release microcapsules NSF, CRH, CHMP4B HTR1A 817/4885HTR6 281/4885TAAR1 1848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.