Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.52 |
| ▸ | CTSL | P07711 | 13/20 | 0.52 |
| ▸ | CTSK | P43235 | 8/20 | 0.48 |
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8283266 | 1.00 | CTSS (0.52) | CTSSCTSLCTSKCTSB | |
| SCHEMBL8283265 | 0.86 | CTSS (0.49) | CTSSCTSLCTSKCTSB | |
| SCHEMBL8284498 | 0.86 | CTSS (0.49) | CTSSCTSLCTSKCTSB | |
| SCHEMBL8283433 | 0.80 | CTSS (0.54) | CTSSCTSLCTSKCTSB | |
| SCHEMBL8283263 | 0.80 | CTSS (0.54) | CTSSCTSLCTSKCTSB | |
| SCHEMBL8283848 | 0.80 | CTSS (0.54) | CTSSCTSLCTSKCTSB | |
| SCHEMBL8282446 | 0.78 | CTSS (0.53) | CTSSCTSK | |
| SCHEMBL6876245 | 0.73 | CTSS (0.64) | CTSSCTSLCTSKCTSB | |
| SCHEMBL8282469 | 0.73 | CTSS (0.54) | CTSSCTSLCTSKCTSB | |
| SCHEMBL8283269 | 0.73 | CTSS (0.54) | CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082876-A1 | C-5 SUBSTITUTED FURANONE DIPEPTIDE CATHEPSIN S INHIBITORS | MEDIVIR UK LTD (GB) | 2005-09-09 | — | — | WO | disclosed |
| WO-2005082876-A1 | C-5 SUBSTITUTED FURANONE DIPEPTIDE CATHEPSIN S INHIBITORS | MEDIVIR UK LTD (GB) | 2005-09-09 | — | — | WO | disclosed |