Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 0.49 |
| ▸ | CTSL | P07711 | 13/20 | 0.46 |
| ▸ | CTSK | P43235 | 8/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8283265 | 1.00 | CTSS (0.49) | CTSSCTSLCTSKCTSBMMP3 | |
| SCHEMBL6509199 | 0.86 | CTSS (0.52) | CTSSCTSLCTSKCTSB | |
| SCHEMBL8283266 | 0.86 | CTSS (0.52) | CTSSCTSLCTSKCTSB | |
| SCHEMBL8283439 | 0.82 | CTSK (0.48) | CTSSCTSLCTSKCTSB | |
| SCHEMBL16257045 | 0.74 | CTSS (0.57) | CTSSCTSLCTSKCTSBMMP3 | |
| SCHEMBL16257052 | 0.74 | CTSS (0.57) | CTSSCTSLCTSKCTSBMMP3 | |
| SCHEMBL16257054 | 0.74 | CTSS (0.60) | CTSSCTSLCTSKCTSBMMP3 | |
| SCHEMBL16257033 | 0.72 | CTSS (0.61) | CTSSCTSLCTSKCTSBMMP3 | |
| SCHEMBL16257040 | 0.72 | CTSS (0.58) | CTSSCTSLCTSKCTSBMMP3 | |
| SCHEMBL16257035 | 0.71 | CTSS (0.55) | CTSSCTSLCTSKCTSBMMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082876-A1 | C-5 SUBSTITUTED FURANONE DIPEPTIDE CATHEPSIN S INHIBITORS | MEDIVIR UK LTD (GB) | 2005-09-09 | — | — | WO | disclosed |