Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.64 |
| ▸ | CTSL | P07711 | 12/20 | 0.63 |
| ▸ | CTSB | P07858 | 3/20 | 0.56 |
| ▸ | CTSK | P43235 | 7/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GRN | P28799 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6874696 | 0.88 | CPB2 (0.55) | CTSSCTSLCTSBCTSKGRN | |
| Lithium Ion SCHEMBL5523630 | 0.86 | CTSS (0.61) | CTSSCTSLCTSBCTSKPKM | |
| SCHEMBL5523884 | 0.83 | CTSS (0.73) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7297694 | 0.82 | CTSS (0.48) | CTSSCTSLCTSBCTSKGRN | |
| SCHEMBL7297681 | 0.82 | CTSS (0.48) | CTSSCTSLCTSBCTSKGRN | |
| SCHEMBL12204063 | 0.82 | CTSS (0.59) | CTSSCTSLCTSBCTSKPKM | |
| SCHEMBL7289965 | 0.81 | MEN1 (0.50) | CTSSCTSLCTSBGRNSORT1 | |
| SCHEMBL5523879 | 0.80 | CTSS (0.66) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1867207 | 0.80 | CTSS (0.54) | CTSSCTSLCTSBCTSKPKM | |
| SCHEMBL6876113 | 0.79 | ALDH1A1 (0.50) | CTSSCTSLSMN1; SMN2GRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452522-A2 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-09-01 | — | — | EP | disclosed |
| EP-0266950-B1 | Nor-statine and nor-cyclostatine polypeptides | PFIZER (US) | 1993-12-29 | — | — | EP | disclosed |
| US-5034376-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-4935405-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |
| US-4814342-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0266950-A2 | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1988-05-11 | — | — | EP | disclosed |