Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502232 | 0.89 | KMT2A (0.50) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL6392368 | 0.86 | CCNA2 (0.41) | KMT2ANPC1RAB9ACDK1CCNB1 | |
| SCHEMBL6388703 | 0.86 | CCNA2 (0.41) | KMT2ANPC1RAB9ACDK1CCNB1 | |
| SCHEMBL6390900 | 0.86 | CCNA2 (0.41) | KMT2ANPC1RAB9ACDK1CCNB1 | |
| SCHEMBL6509220 | 0.85 | NPC1 (0.48) | KMT2ANPC1RAB9AEPHX1PRMT3 | |
| SCHEMBL6500692 | 0.84 | RAB9A (0.52) | KMT2ANPC1RAB9AMEN1TP53 | |
| SCHEMBL6505267 | 0.83 | ATM (0.41) | NPC1RAB9ASMN1; SMN2GAAKDM4E | |
| SCHEMBL6388927 | 0.83 | KDM4E (0.41) | KMT2ANPC1RAB9AMEN1GAA | |
| SCHEMBL6504984 | 0.82 | SMN1; SMN2 (0.44) | NPC1RAB9ACDK1CCNB1CCNA2 | |
| SCHEMBL6387573 | 0.82 | SMN1; SMN2 (0.44) | NPC1RAB9ACDK1CCNB1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | KMT2A 3213/4885NPC1 277/4885RAB9A 2649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.