Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | USP14 | P54578 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509282 | 0.87 | PTGDR2 (0.69) | PTGDR2AKR1B1USP14 | |
| SCHEMBL3556759 | 0.83 | PTGDR2 (0.77) | PTGDR2AKR1B1CA12CA1CA2 | |
| SCHEMBL6512107 | 0.82 | PTGDR2 (0.50) | PTGDR2AKR1B1CA12CA1CA2 | |
| SCHEMBL6516793 | 0.78 | PTGDR2 (0.54) | PTGDR2AKR1B1 | |
| SCHEMBL3557583 | 0.78 | PTGDR2 (0.59) | PTGDR2AKR1B1CA12CA1CA2 | |
| SCHEMBL6511562 | 0.77 | PTGDR2 (0.44) | PTGDR2AKR1B1USP14KDM4ETUBB4A | |
| SCHEMBL14253022 | 0.72 | CA12 (0.47) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL1385122 | 0.71 | PTGDR2 (0.87) | PTGDR2AKR1B1 | |
| SCHEMBL6509296 | 0.71 | PTGDR2 (0.41) | PTGDR2AKR1B1CA12CA1CA2 | |
| SCHEMBL3017306 | 0.70 | PTGDR2 (0.70) | PTGDR2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121141-A1 | PYRROLOPYRIDINE DERIVATIVES AND USE THEREOF FOR TREATING DISEASES MEDIATED BY PROSTAGLANDIN D2 (PGD2) | OXAGEN LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |