Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6395604 | 0.81 | SMN1; SMN2 (0.41) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL6511441 | 0.81 | — | — | |
| SCHEMBL12092712 | 0.78 | MEN1 (0.34) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL3279481 | 0.78 | MEN1 (0.39) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL6511005 | 0.69 | LMNA (0.31) | LMNA | |
| SCHEMBL8197545 | 0.68 | SLC6A3 (0.37) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL6899822 | 0.68 | — | — | |
| SCHEMBL6512880 | 0.68 | LMNA (0.39) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL6510631 | 0.67 | LMNA (0.33) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL6508420 | 0.67 | LMNA (0.31) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005068420-A1 | UREA AND THIOUREA COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2005-07-28 | — | — | WO | claimed |