Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509705 | 0.89 | LMNA (0.32) | LMNA | |
| SCHEMBL6391462 | 0.80 | RAB9A (0.37) | LMNA | |
| SCHEMBL6510631 | 0.79 | LMNA (0.33) | LMNA | |
| SCHEMBL8745049 | 0.78 | SSTR4 (0.33) | — | |
| SCHEMBL6515537 | 0.78 | LMNA (0.31) | LMNA | |
| SCHEMBL6508420 | 0.78 | LMNA (0.31) | LMNA | |
| SCHEMBL2737103 | 0.77 | ACACB (0.35) | LMNA | |
| SCHEMBL6898799 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL314331 | 0.70 | LMNA (0.38) | LMNA | |
| SCHEMBL6512880 | 0.68 | LMNA (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005068420-A1 | UREA AND THIOUREA COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2005-07-28 | — | — | WO | claimed |
| WO-2005068420-A1 | UREA AND THIOUREA COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2005-07-28 | — | — | WO | disclosed |