Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.81 |
| ▸ | MAPT | P10636 | 10/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.77 |
| ▸ | HPGD | P15428 | 5/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CASP1 | P29466 | 2/20 | 0.59 |
| ▸ | CASP7 | P55210 | 2/20 | 0.59 |
| ▸ | AHR | P35869 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509340 | 0.92 | KDM4E (0.70) | KDM4EMAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL6511778 | 0.90 | KDM4E (0.74) | KDM4EMAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL6507754 | 0.87 | KMT2A (0.68) | KDM4EMAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL16299047 | 0.87 | KDM4E (0.67) | KDM4EMAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL6511759 | 0.83 | KDM4E (0.73) | KDM4EMAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL6509689 | 0.77 | KMT2A (0.78) | KDM4EMAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL6510561 | 0.74 | ALDH1A1 (0.68) | KDM4EMAPTALDH1A1HPGDL3MBTL1 | |
| SCHEMBL31647264 | 0.71 | MAPT (0.64) | KDM4EMAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL5532732 | 0.70 | KDM4E (0.90) | KDM4EMAPTALDH1A1HPGDL3MBTL1 | |
| SCHEMBL3971612 | 0.70 | EGFR (0.51) | KDM4EMAPTALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005087742-A1 | METABOLIC KINASE MODULATORS AND METHODS OF USE AS PESTICIDES | EXELIXIS, INC. (US) | 2005-09-22 | — | — | WO | claimed |