Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510768 | 0.93 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1HPGDMEP1BTHRA | |
| SCHEMBL6508797 | 0.90 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1HPGDMEP1BTHRA | |
| SCHEMBL6510665 | 0.90 | MEP1B (0.39) | ALDH1A1L3MBTL1HPGDMEP1BTHRA | |
| SCHEMBL6509550 | 0.87 | MEP1B (0.42) | ALDH1A1L3MBTL1HPGDMEP1BPTGES | |
| SCHEMBL6509513 | 0.86 | SLC6A9 (0.41) | ALDH1A1L3MBTL1HPGDMEP1BEGFR | |
| SCHEMBL6511874 | 0.86 | AKR1B1 (0.43) | ALDH1A1L3MBTL1HPGDTHRATHRB | |
| SCHEMBL6511152 | 0.86 | ALDH1A1 (0.45) | ALDH1A1HPGDPTGESLMNAMEN1 | |
| SCHEMBL6516317 | 0.85 | FFAR4 (0.39) | ALDH1A1L3MBTL1HPGDMEP1BTHRA | |
| SCHEMBL6511963 | 0.84 | MEP1B (0.47) | MEP1BMEN1KMT2AKDM4E | |
| SCHEMBL6518329 | 0.83 | NPC1 (0.39) | ALDH1A1L3MBTL1HPGDMEP1BEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |