SCHEMBL6509388

SCHEMBL6509388

COC(=O)Oc1ccc2cc3ccccc3cc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.51
MAPT P10636 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
CYP1A2 P05177 1/20 0.48
CYP2A6 P11509 1/20 0.48
KDM4E B2RXH2 2/20 0.46
HSD17B10 Q99714 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 1/20 0.46
ESR1 P03372 1/20 0.46
RECQL P46063 1/20 0.46
BCHE P06276 1/20 0.45
FAAH O00519 1/20 0.45
EPHX1 P07099 1/20 0.45
PPARG P37231 3/20 0.44
PPARA Q07869 3/20 0.44
PPARD Q03181 1/20 0.44
NPC1 O15118 2/20 0.44
CASP3 P42574 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14514195 0.94 KMT2A (0.58) KMT2AMEN1MAPTTDP1CYP1A2
SCHEMBL2944091 0.90 KDM4E (0.47) KMT2AMEN1MAPTTDP1CYP1A2
SCHEMBL7180001 0.83 KDM4E (0.46) KMT2AMEN1MAPTTDP1CYP1A2
SCHEMBL7081125 0.82 KMT2A (0.57) KMT2AMEN1MAPTTDP1CYP1A2
SCHEMBL1809377 0.82 KMT2A (0.66) KMT2AMEN1MAPTTDP1CYP1A2
SCHEMBL13422218 0.81 CYP2A6 (0.48) KMT2ATDP1CYP1A2CYP2A6L3MBTL1
SCHEMBL7767575 0.81 KMT2A (0.52) KMT2AMEN1MAPTCYP1A2ESR1
SCHEMBL28876060 0.81 PDGFRB (0.56) KMT2AMEN1MAPTTDP1KDM4E
SCHEMBL10437567 0.81 PDGFRB (0.56) KMT2AMEN1MAPTTDP1KDM4E
SCHEMBL26628646 0.81 PDGFRB (0.56) KMT2AMEN1MAPTTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050269563-A1 Fullerodendrimer-comprising film ECODEVICE LABORATORY CO., LTD. (JP) 2005-12-08 US disclosed
US-20040175568-A1 Can be applied to organic semiconductor devices utilizing the optophysicochemical characteristics of fullerene, and in particular, to solar panel materials, organic EL materials, photorefractive polymers, electrophotographic light-sensitive materials, film materials having environmental cleansing actions ECODEVICE LABORATORY CO., LTD. (JP) 2004-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050269563-A1 Fullerodendrimer-comprising film TOMM70, SCO2, S100A10 KMT2A 3662/4885MEN1 3213/4885MAPT 427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.