Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6518055 | 0.82 | IDO1 (0.45) | ALDH1A1SMN1; SMN2PKMGAAIDO1 | |
| SCHEMBL6510310 | 0.82 | IDO1 (0.45) | ALDH1A1SMN1; SMN2PKMGAAIDO1 | |
| SCHEMBL17230505 | 0.82 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2PKMGAAIDO1 | |
| SCHEMBL6512047 | 0.81 | IDO1 (0.46) | ALDH1A1SMN1; SMN2PKMGAAIDO1 | |
| SCHEMBL6511575 | 0.80 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2PKMGAAACE | |
| SCHEMBL6511578 | 0.80 | TAAR1 (0.47) | ALDH1A1SMN1; SMN2PKMIDO1MAPT | |
| SCHEMBL6512863 | 0.80 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2PKMGAAIDO1 | |
| SCHEMBL8003157 | 0.79 | CYP2C19 (0.64) | ALDH1A1SMN1; SMN2PKMGAALDHA | |
| SCHEMBL10791043 | 0.77 | FFAR1 (0.54) | SMN1; SMN2LDHAMAPTFFAR1 | |
| SCHEMBL498480 | 0.76 | CYP1A2 (0.67) | ALDH1A1SMN1; SMN2PKMGAALDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050192430-A1 | Linker arms for nanocrystals and compounds thereof | ROSENTHAL SANDRA J (US) | 2005-09-01 | — | — | US | disclosed |
| US-20030129590-A1 | Linker arms for nanocrystals and compounds thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-07-10 | — | — | US | disclosed |
| WO-2001090716-A2 | LINKER ARMS FOR NANOCRYSTALS AND COMPOUNDS THEREOF | VANDERBILT UNIVERSITY (US) | 2001-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030129590-A1 | Linker arms for nanocrystals and compounds thereof | SCO2, NCL, NCAPH | ALDH1A1 2277/4885SMN1; SMN2 1359/4885PKM 3276/4885 |
| US-20050192430-A1 | Linker arms for nanocrystals and compounds thereof | NCL, CHN2, SCO2 | ALDH1A1 3030/4885SMN1; SMN2 1903/4885PKM 4211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.