SCHEMBL65097

SCHEMBL65097

O=C(O)O[C@H](COP(=O)(O)O)[C@H](O)[C@H](O)COP(=O)(O)O

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PGD P52209 5/20 0.55
PGK1 P00558 1/20 0.48
PGK2 P07205 1/20 0.48
MPI P34949 1/20 0.46
LPAR6 P43657 1/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR4 Q99677 1/20 0.33
LPAR5 Q9H1C0 1/20 0.33
LPAR2 Q9HBW0 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20855306 0.90 PGD (0.47) PGDPGK1PGK2MPI
SCHEMBL13179933 0.88 PGD (0.46) PGDPGK1PGK2MPILPAR6
SCHEMBL5000804 0.78 PGD (0.61) PGDPGK1PGK2MPILPAR5
SCHEMBL16416132 0.78 PGD (0.61) PGDPGK1PGK2MPILPAR5
SCHEMBL4330442 0.76 PGD (0.78) PGDPGK1PGK2MPILPAR5
SCHEMBL20475910 0.76 PGD (0.78) PGDPGK1PGK2MPILPAR5
SCHEMBL20475925 0.76 PGD (0.78) PGDPGK1PGK2MPILPAR5
SCHEMBL4330445 0.76 PGD (0.78) PGDPGK1PGK2MPILPAR5
SCHEMBL20475921 0.74 PGD (0.58) PGDPGK1PGK2MPI
SCHEMBL11023777 0.74 PGD (0.75) PGDPGK1PGK2MPILPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2631241-B1 PROCESS FOR GENERATION OF PROTEIN AND USES THEREOF UNIV AUSTRALIAN NATIONAL (AU) 2018-09-12 EP disclosed
US-10041058-B2 Process for generation of protein and uses thereof THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2018-08-07 US disclosed
EP-2079755-B1 PROCESS FOR GENERATION OF PROTEIN AND USES THEREOF THE AUSTRALIAN NAT UNIV (AU) 2017-08-30 EP disclosed
US-20170152499-A1 PROCESS FOR GENERATION OF PROTEIN AND USES THEREOF THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2017-06-01 US disclosed
US-9598688-B2 Process for generation of protein and uses therof THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2017-03-21 US disclosed
EP-2631241-A2 Process for generation of protein and uses thereof The Australian National University (AU) 2013-08-28 EP disclosed
US-8129512-B2 Using increased ribulose 1,5-bisphosphate carboxylase/oxygenase (Rubisco) activity as reporter function indicating regenerated photosynthetic and production processes in plants PIONEER HI-BRED INTERNATIONAL, INC. (US) 2012-03-06 US disclosed
US-7745186-B2 Ribulose, 1,5-bisphosphate carboxylase/oxygenase polypeptides and related polynucleotides CODEXIS, INC. (US) 2010-06-29 US disclosed
US-20090203532-A1 PROCESS FOR GENERATION OF PROTEIN AND USES THEROF THE AUSTRALIAN NATINAL UNIVERSITY (AU) 2009-08-13 US disclosed
EP-2079755-A1 PROCESS FOR GENERATION OF PROTEIN AND USES THEREOF The Australian National University (AU) 2009-07-22 EP disclosed
US-20090162895-A1 RIBULOSE, 1,5-BISPHOSPHATE CARBOXYLASE/OXYGENASE POLYPEPTIDES AND RELATED POLYNUCLEOTIDES CODEXIS, INC. (US) 2009-06-25 US disclosed
US-20080256666-A1 METHODS OF IDENTIFYING AND CREATING RUBISCO LARGE SUBUNIT VARIANTS WITH IMPROVED RUBISCO ACTIVITY, COMPOSITIONS AND METHODS OF USE THEREOF PIONEER HI-BRED INTERNATIONAL, INC. (US) 2008-10-16 US disclosed
WO-2008043147-A1 PROCESS FOR GENERATION OF PROTEIN AND USES THEREOF THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2008-04-17 WO disclosed
US-7351562-B2 Ribulose 1,5-bisphosphate carboxylase/oxygenase polypeptides and related polynucleotides CODEXIS, INC. (US) 2008-04-01 US disclosed
US-20040038262-A1 Ribulose 1,5-bisphosphate carboxylase/oxygenase polypeptides and related polynucleotides CODEXIS, INC. 2004-02-26 US disclosed