Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17919856 | 0.79 | HTR1B (0.51) | EGFRHTR1BHTR1DMCHR1SLC6A4 | |
| SCHEMBL15565685 | 0.76 | HTR1B (0.49) | MAPTEGFRHTR1BHTR1DMCHR1 | |
| SCHEMBL6585052 | 0.73 | MEN1 (0.40) | LMNASMN1; SMN2MAPTATMNPC1 | |
| SCHEMBL27674309 | 0.73 | CNR1 (0.41) | LMNASMN1; SMN2HTR1BHTR1DMCHR1 | |
| SCHEMBL9322884 | 0.73 | GAA (0.40) | HTR1BHTR1DMCHR1NPC1 | |
| SCHEMBL6121483 | 0.73 | NCEH1 (0.38) | LMNAEGFRRXFP1CASP1CASP3 | |
| SCHEMBL6312903 | 0.71 | KDM4E (0.51) | LMNASMN1; SMN2EGFRRXFP1ACHE | |
| SCHEMBL16417118 | 0.70 | CYP1A2 (0.56) | MAPTACHEMCHR1 | |
| SCHEMBL6585059 | 0.70 | MGLL (0.43) | LMNASMN1; SMN2MAPTNPC1 | |
| SCHEMBL20744686 | 0.69 | BCHE (0.45) | HTR1BHTR1DMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005108338-A1 | NOVEL THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER, METABOLIC DISEASES AND SKIN DISORDERS | AUSPEX PHARMACEUTICALS (US) | 2005-11-17 | — | — | WO | disclosed |