Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504279 | 0.81 | HSD11B1 (0.51) | EPHX1CNR2GBA1 | |
| SCHEMBL6506890 | 0.77 | EPHX1 (0.55) | EPHX1ALDH1A1CNR2KDM4EHPGD | |
| SCHEMBL6508426 | 0.76 | EPHX1 (0.52) | EPHX1CNR2GBA1 | |
| SCHEMBL6502476 | 0.73 | HSD11B1 (0.57) | EPHX1CNR2KMT2A | |
| SCHEMBL6503334 | 0.72 | ALDH1A1 (0.42) | ALDH1A1SIGMAR1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL9892004 | 0.71 | CNR2 (0.54) | EPHX1ALDH1A1CNR2KDM4EGBA1 | |
| SCHEMBL9891991 | 0.71 | CNR2 (0.54) | EPHX1ALDH1A1CNR2KDM4EGBA1 | |
| SCHEMBL6502473 | 0.68 | EPHX1 (0.46) | EPHX1ALDH1A1CNR2KMT2A | |
| SCHEMBL9891989 | 0.68 | CNR2 (0.51) | EPHX1ALDH1A1CHRM3CHRM5SIGMAR1 | |
| SCHEMBL9892002 | 0.68 | CNR2 (0.51) | EPHX1ALDH1A1CHRM3CHRM5SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261290-A1 | Novel compounds of proline and morpholine derivatives | CHENG HENGMIAO | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261290-A1 | Novel compounds of proline and morpholine derivatives | CYP11B1, HSD11B1, CYP11B2 | EPHX1 810/4885ALDH1A1 114/4885CHRM3 2423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.