SCHEMBL6509954

SCHEMBL6509954

OC(c1ccc(I)cc1)c1cc(I)cc(I)c1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP19A1 P11511 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
GSK3B P49841 1/20 0.31
TPMT P51580 1/20 0.31
ACACB O00763 1/20 0.31
ELANE P08246 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14160109 0.87 CYP17A1 (0.38) CYP17A1CYP3A4CYP19A1CYP11B1CYP11B2
SCHEMBL9440465 0.78 CYP3A4 (0.52) CYP17A1CYP3A4CYP19A1CYP11B1CYP11B2
SCHEMBL24238297 0.78 SMN1; SMN2 (0.48) CA1CA2
SCHEMBL14160116 0.76 MLKL (0.40) CYP3A4ACACBELANE
SCHEMBL9440341 0.76 HTR2A (0.42)
SCHEMBL9576929 0.72 HDAC8 (0.41) CYP3A4GSK3BTPMTCA1CA2
SCHEMBL21708803 0.71 TPMT (0.38) GSK3BTPMTACACBCA1CA2
SCHEMBL11602426 0.71 TPMT (0.38) GSK3BTPMTACACBCA1CA2
SCHEMBL9016042 0.68 CYP2D6 (0.41) CYP3A4CA1CA2
SCHEMBL1625341 0.67 NOS3 (0.45) GSK3BTPMTACACBCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050101063-A1 Three-terminal field-controlled molecular devices TOUR JAMES M (US) 2005-05-12 US disclosed
WO-2002035580-A2 THREE-TERMINAL FIELD-CONTROLLED MOLECULAR DEVICES MOLECULAR ELECTRONICS CORPORATION (US) 2002-05-02 WO disclosed