Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | HTR1B | P28222 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.48 |
| ▸ | ICMT | O60725 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3223154 | 0.83 | TRPV1 (0.55) | KDM4ETSHRNFKB1PMP22NPSR1 | |
| Oxalic Acid SCHEMBL2540213 | 0.82 | CYP1A2 (0.68) | KDM4ETSHRCYP2C9NFKB1PMP22 | |
| SCHEMBL674415 | 0.82 | KDM4E (1.00) | KDM4ETSHRCYP2C9ALDH1A1LMNA | |
| SCHEMBL4501048 | 0.82 | KDM4E (0.74) | KDM4ETSHRCYP2C9ALDH1A1LMNA | |
| SCHEMBL1379245 | 0.81 | KDM4E (0.50) | KDM4ETSHRCYP2C9ALDH1A1LMNA | |
| SCHEMBL25282407 | 0.81 | TRPV1 (0.69) | KDM4EALDH1A1HPGDPMP22TRPV1 | |
| SCHEMBL9662031 | 0.81 | CYP2D6 (0.68) | TSHRCYP2C9NFKB1PMP22NPSR1 | |
| SCHEMBL31375050 | 0.80 | NR4A2 (0.55) | KDM4EALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL24855664 | 0.80 | TRPV1 (0.49) | KDM4ETSHRNFKB1PMP22NPSR1 | |
| SCHEMBL15747755 | 0.80 | KDM4E (0.75) | KDM4ETSHRCYP2C9ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050203166-A1 | Indole-3-acetic acid derivatives | CANCER RESEARCH TECHNOLOGY LIMITED | 2005-09-15 | — | — | US | disclosed |
| US-6890948-B1 | Use of indole-3-acetic acid derivatives in medicine | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2005-05-10 | — | — | US | disclosed |
| EP-1296676-B1 | USE OF INDOLE-3-ACETIC ACID DERIVATIVES IN MEDICINE | CANCER REC TECH LTD (GB) | 2004-01-28 | — | — | EP | disclosed |
| EP-1296676-A1 | USE OF INDOLE-3-ACETIC ACID DERIVATIVES IN MEDICINE | Cancer Research Technology Limited (GB) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002002110-A1 | USE OF INDOLE-3-ACETIC ACID DERIVATIVES IN MEDICINE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2002-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203166-A1 | Indole-3-acetic acid derivatives | ADCY3, GPR3, HCAR3 | KDM4E 1795/4885TSHR 823/4885CYP2C9 2407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.